National Reye's Syndrome Foundation's Gifting Site

Where Kids and Aspirin Products Don't Mix

What is Reye's Syndrome?

Reye's Syndrome is a disease which affects all organs of the body, but most lethally the liver and the brain. Reye's Syndrome is a two-phase illness because it is almost always associated with a previous viral infection, such as influenza, cold, or chicken pox. Scientists do know that Reye's Syndrome is not contagious and the cause is unknown. Reye's Syndrome is often misdiagnosed as encephalitis, meningitis, diabetes, drug overdose, poisoning, Sudden Infant Death Syndrome, or psychiatric illness.

While the cause and cure remain unknown, research has established a link between Reye's Syndrome and the use of aspirin and other salicylate containing medications, over the counter products, and topical use products.

In 1974, the National Reye's Syndrome Foundation was incorporated, becoming the first citizen group to generate a concerted, organized lay movement to eradicate Reye's Syndrome.

Reye's Syndrome tends to appear with greatest frequency during January, February, and March when influenza is most common. Cases are reported in every month of the year. An epidemic of flu or chicken pox is commonly followed by an increase in the number of cases of Reye's Syndrome.

When Reye's Syndrome develops, it typically occurs when a person is beginning to recover from a viral illness. Abnormal accumulations of fat begin to develop in the liver and other organs of the body, along with a severe increase of pressure in the brain. Unless diagnosed and treated successfully, death is common, often within a few days. A person's life depends upon early diagnosis. Statistics indicate an excellent chance of recovery when Reye's Syndrome is diagnosed and treated in its earliest stages. The later the diagnosis and treatment, the more severely reduced are chances for successful recovery and survival.

Reye's Syndrome Symptoms Include:

  • Persistent or continuous vomiting
  • Signs of brain dysfunction
  • Listlessness, Loss of pep and energy, Drowsiness
  • Personality changes
  • Irritability, Aggressive behavior
  • Disorientation, Confusion, Irrational behavior, Combative
  • Delirium, Convulsions, Coma

Reye's Syndrome should be suspected in a person if this pattern of symptoms appear during, or most commonly, after a viral illness. Not all of the symptoms have to occur, nor do they have to be displayed in this order. Fever is not usually present. Many diseases have symptoms in common. Physicians and medical staff in emergency rooms who have not had experience in treating Reye's Syndrome may misdiagnose the disease. The symptoms of Reye's Syndrome in infants do not follow a typical pattern. For example, vomiting may be replaced with diarrhea, and they may display irregular breathing.

For more indepth information about Reye's Syndrome see www.ReyesSyndrome.Org